pharmacokinetics study
Service items
■ LC-MS analysis of biological samples
■ Protein binding research
■ CYP450 enzyme induction test
■ CYP450 enzyme inhibition test
■ Metabolic phenotype study (RAF method)
■ Metabolic stability study
■ Tissue distribution test
■ Glutathione capture test
■ Permeability study (Caco-2 model)
■ Protein binding research
■ CYP450 enzyme induction test
■ CYP450 enzyme inhibition test
■ Metabolic phenotype study (RAF method)
■ Metabolic stability study
■ Tissue distribution test
■ Glutathione capture test
■ Permeability study (Caco-2 model)
Service advantages
>Jugular sinus blood collection technology: animals do not need anesthesia, have little trauma, conform to animal ethics, and can meet PK/TK blood collection requirements.
>Bile duct cannulation technology in conscious rats: bile duct cannulation and external catheterization can be used to collect bile in conscious rats for more than 72 hours.
>Cerebrospinal fluid collection technology: It can collect the cerebrospinal fluid of conscious/anesthetized animals for the study of blood-brain barrier permeability.
>Bile duct cannulation technology in conscious rats: bile duct cannulation and external catheterization can be used to collect bile in conscious rats for more than 72 hours.
>Cerebrospinal fluid collection technology: It can collect the cerebrospinal fluid of conscious/anesthetized animals for the study of blood-brain barrier permeability.
