Shandong Xinbo passed the 2025 bone marrow micronucleus morphological examination capability verification activity held by the China National Institute for Food and Drug Control with "satisfactory" results!
This is not only a hardcore certification of Shandong Xinbo's technological strength, but also means that we can provide more reliable genetic toxicity data support for pharmaceutical companies and research and development institutions, greatly reducing the risks in the drug development process!

Jinan Laboratory

Linyi Laboratory

Full scene coverage, adaptable to various research and development needs
Whether it is conventional small molecule drugs, special peptide drugs, or genetic toxicity screening of drug impurities, Shandong Xinbo can provide targeted solutions, with core trial projects covering:
＞Ames test: the classic gold standard for mutation screening, which quickly detects the risk of genetic mutations in bacteria caused by the test substance;
＞In vitro mammalian cell chromosome aberration test: visually observe abnormal cell chromosome structure and accurately evaluate in vitro genetic toxicity;
In vitro mouse lymphoma cell Tk gene mutation assay: Focusing on somatic gene mutations, providing key data for drug safety evaluation;
＞Mammalian micronucleus test: Evaluate the chromosomal damage effect of the test substance on bone marrow cells through in vivo detection;
＞Mouse spermatogonial chromosome aberration test: Special attention is paid to the genetic toxicity of germ cells to safeguard the reproductive safety of drugs;
＞In vitro micronucleus test: an efficient in vitro detection system, shortening the test cycle, and adapting to the needs of rapid screening;
＞Mini Ames test: a simplified version of the mutagenicity detection tool, suitable for low-dose samples or rapid early evaluation.

Four major hard core advantages: from team to laboratory, guarding every aspect of test quality
✅ Senior team leader: The project leader has over 10 years of experience in genetic toxicity testing, from scheme design to data review, with professional control throughout the entire process to avoid trial pitfalls;
✅ Customized scheme design: not only understand experiments, but also drug development - tailor experimental schemes for different categories such as conventional drugs, peptide drugs, drug impurities, etc;
✅ High end equipment support: advanced instruments such as fluorescence biological microscopes, carbon dioxide incubators, and biosafety cabinets are fully equipped to provide "hardware guarantees" for experimental accuracy;
✅ GLP standard laboratory: The cell room and microbiology room strictly follow GLP management standards, operate in different zones, prevent cross contamination, and ensure that each set of data is authentic and reliable.

Shandong Xinbo was established in April 2010, with Jinan Laboratory and Linyi Laboratory. It is a national high-tech enterprise, Shandong Enterprise Technology Center, Shandong Gazelle Enterprise, and a research service-oriented enterprise that integrates pharmacological research, toxicology research, drug analysis and testing services, animal pathology testing, and medical device evaluation services. We have completed preclinical safety evaluations for over 400 innovative drugs, including chemical drugs, traditional Chinese medicine and natural medicines, biological products, preventive and therapeutic vaccines, monoclonal antibodies, cell therapy products, medical devices, and other varieties.